2022

1. Macdonald, L.;  Taylor, G. C.;  Brisbane, J. M.;  Christodoulou, E.;  Scott, L.;  von Kriegsheim, A.;  Rossant, J.;  Gu, B.; Wood, A. J., Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons. Elife 2022, 11.

This paper describes the proof of concept study demonstrating using the Auxin Inducible Degradation system for manipulating endogenous proteins in live mice.

2. Gu, B.;  Bradshaw, B.;  Zhu, M.;  Sun, Y.;  Hopyan, S.; Rossant, J., Live imaging YAP signalling in mouse embryo development. Open Biology 2022, 12 (1), 210335.

This paper describes the first knock-in reporter model for imaging dynamic Yap signaling in mice.

2018

1. Gu, B.;  Posfai, E.; Rossant, J., Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos. Nat Biotechnol 2018, 36 (7), 632-637.

This paper describes the 2C-HR-CRISPR technology for efficiently generating large fragment knock-in mouse models.

Check full publication list:

https://www.ncbi.nlm.nih.gov/myncbi/10maEWgzL5jgRx/bibliography/public/